# CNS Curative Technologies, LLC > Admin Email: wordpress.development.team@gmail.com ## Posts ### Blog 1 Lorem Ipsum is simply dummy text...... ### Blog 2 Lorem Ipsum is simply dummy text.... ### Blog 3 Lorem Ipsum is simply dummy text.... ### Blog 4 Lorem Ipsum is simply dummy text....  ## Pages ### Shop Home ### Locations Home CNS Curative Technologies, LLC 300 East 2nd street, 15th floor, 1510, suite 1512, Reno, Nevada, 89501 ### Checkout ### Cart ### My account ### Shop ### Lyme Disease Home Lyme Disease Lyme disease is a serious condition that can impact your quality of life. Early detection and treatment are crucial. At CNS Curative Technologies, we're committed to raising awareness and providing effective solutions to combat this disease. Understanding Lyme Disease Caused by the bacterium Borrelia burgdorferi, Lyme disease spreads through the bite of infected ticks, leading to symptoms such as fever, headache, fatigue, and erythema migrans rash. Untreated, it can affect joints, the heart, and the nervous system. Understanding its stages and symptoms is crucial for effective management and treatment. Treatment Options Conventional treatments like antibiotics are common, but innovative solutions can offer additional benefits. Our NeuroClimax® is designed to support brain health and improve cognitive function, which is often impacted by Lyme disease cognitive decline. Our comprehensive approach to Lyme disease treatment in Nevada combines traditional and innovative treatments, leading to better outcomes. Prevention Strategies Preventing Lyme disease is easier than treating it. Simple steps like using insect repellent, wearing protective clothing, and checking for ticks after outdoor activities can make a big difference. Protect yourself and your loved ones with these effective prevention strategies. Living with Lyme Disease Managing chronic Lyme disease symptoms can be challenging. Our products, including NeuroClimax®, provide support for brain health and overall well-being. Stay informed and find the best integrative approaches to care that work for you, especially if you experience cognitive decline in Lyme disease. Latest Research and Developments Stay updated with the latest research and developments in Lyme disease treatment. Our team at CNS Curative Technologies is dedicated to advancing treatments and improving prevention strategies through ongoing research and innovation. ### Lyme disease florida Home Contact Us for Premier Florida Lyme Disease Treatment Dealing with Lyme disease in Florida? Our solutions, including NeuroClimax®, offer a breakthrough in symptom relief and brain health. NeuroClimax® is an advanced intranasal nutraceutical, expertly formulated to enhance cognitive function and improve well-being. Reach out to us and experience our proven, effective treatments designed to help you reclaim your life from Florida Lyme disease. ### Lyme disease Arizona Home Advanced Lyme Disease Treatment in Arizona with NeuroClimax® Lyme disease in Arizona is becoming more common these days. Discover our advanced treatment solutions featuring NeuroClimax®, our innovative intranasal nutraceutical. Engineered to optimize brain function, NeuroClimax® effectively alleviates symptoms and supports cognitive health. Utilize our scientifically validated formula to enhance your quality of life and regain control over Lyme disease symptoms. ### Parkinson disease Florida Home Discover Hope Through Innovation Parkinson's disease in Florida is a growing challenge, but there's reason for optimism. At CNS Curative Technologies, we're dedicated to fostering brain health through professional research.We specialize in developing and manufacturing revolutionary, scientifically-validated intranasal nutraceuticals like NeuroClimax®. This innovative solution is designed to optimize brain function and support symptom management for Parkinson's patients in Florida. Reclaiming Control Over Your Well-Being NeuroClimax® utilizes an advanced intranasal delivery system for enhanced absorption and targeted effects. Partner with us, a leading Parkinson's disease specialist in Florida, to explore how NeuroClimax® can support your path toward a brighter future. ### Legal Home Nevada state business IDNV20201751927 Nevada Entity IDE5821562020-4 Proprietary Formulations Tradesecrets NeuroClimax, NeuroClimax advanced, NeuroClimax Gold CNS Curative Technologies provisional patentNo. 63/897,520US Patent options agreementNVRIC-OPTN-25-CNSCurative Federal ID Number85-0580189 UENHMXYLDA8SAZ5 Trademarks 983090889830909998309108 Intellectual Property U.S. Provisional Patent Application No. 63/897,520Title: TREATMENT OF COGNITIVE DECLINE AND FATIGUE WITH INTRANASAL NOOTROPIC FORMULATIONSFirst Named Inventor: Raul Y. DagdaCNS Curative Technologies LLCRef.: FHW081752  ### Market insights and Product Pipeline Home Nootropics Space APR is 14.4%, equivalent to $5 billion Specific Product Costs Varying from $70-85 per kit for certain applications up to $250 per kit for others. PD & Cognitive Decline Market Parkinson’s Disease:$3.4 billion period as of 2022Cognitive decline:$ 2.2 billion as of 2021 Anticipated Expansion Projections suggest potential annual sales for us ranging from $ 500k to 1.5 million within the first 6 months upon product commercialization in 2024 UNLOCK OPPORTUNITIES: MAKE A CHANGE WITH CNS CURATIVE TECHNOLOGIES CCT is actively seeking investors who are interested in being part of our dynamic pipeline of products. We invite you to explore investment opportunities with us. If you are interested, please don't hesitate to contact us atInvestorrelations@cnscurative.comWe’re open to seed stage investment transitioning into feasibility manufacture development of prototypes. After, CCT will phase in immediately into manufacture of pilot scale batch (March to August) 2024) into go to market product launch 3 months and, commercial scale on demand e-commerce sales (after September 2024) ### Wellness & Aging According to the National Coffee Association about 150 million Americans consume coffee daily, while approximately one-third of teenagers and young adults regularly consume energy drinks in the United States.​ Home While many people typically turn to coffee, energy drinks like RedBull and Monster, and other stimulants such as nicotine for a morning boost, our unique product offers an alternative. It’s cost-effective, not caffeine-based, and avoids inducing the agitation or palpitations associated with coffee while promoting brain health. Drawing upon existing literature on active ingredients and our own research conducted on cultured neurons and animal models, our product, NeuroClimax, is anticipated to provide the following benefits for the brain Increase the levels of neurotrophic factors Brain-Derived Neurotrophic Factor and Nerve Growth Factor which are known to simulate brain-protective signaling pathways Increase the levels of energy in the brain since it is known that a high level of BDNF stimulates oxidative phosphorylation and the production of ATP in neurons An increase in the level of BDNF helps with consolidating long term memories by increasing neuronal activity and plasticity leading to more brain health Cyclic amp enhancer and glutaminergic agonists of memory receptors are well characterized nootropic compounds, compounds that stimulate cognitive skills and neuronal activity Can increase the level of energy in the body via the synthesis of BDNF in the brain and its release from the brain to muscle Cyclic AMP enhancers such as Forskolin activates cyclic AMP-dependent neuronal pathways to stimulate the production of BDNF and synaptic plasticity Glutaminergic peptide agonists of memory receptors have been characterized to stimulate AMPA receptors and activate neuronal survival pathways These compounds are deemed safe and non-toxic at commercially-available doses with little side effects ### Parkinson's Disease Home Understanding Parkinson's Disease Parkinson's disease is a progressive neurological disorder that affects movement. It commonly manifests through symptoms such as tremors, stiffness, slowness of movement, and difficulties with balance. This condition results from the gradual loss of dopamine-producing neurons in the brain. Causes and Risk Factors The exact cause of Parkinson's disease is still unknown, but it is believed to involve a combination of genetic and environmental factors. Age is a significant risk factor, with most cases occurring in individuals over 60 years old. However, younger adults can also develop Parkinson's disease due to genetic mutations or other factors. Diagnosis and Early Detection Diagnosing Parkinson's disease involves a thorough clinical evaluation by a neurologist. Symptoms such as tremors, rigidity, and bradykinesia (slowness of movement) are assessed. Imaging tests like MRI and CT scans may be used to rule out other conditions and confirm the diagnosis. Early detection allows for the timely initiation of Parkinson's disease treatment in Nevada, which can significantly improve outcomes. Comprehensive Treatment Approaches CNS Curative Technologies LLC stands at the forefront of research and development in cognitive enhancement, offering a breakthrough solutions for individuals managing Parkinson's disease in older adults and Parkinson's disease in younger adults, aids in symptom alleviation and supports cognitive health effectively. Leverage innovative intranasal nootropic formulation developments for enhancing quality of life and regain control over Parkinson's symptoms.The science and technology NeuroClimax's pre-clinical articles - Ruben & Dagda, Raul & Mayorga, Emmanuel & Martinez, Bridget & Gallahue, Aine. (2022). Intranasal Administration of Forskolin and Noopept Reverses Parkinsonian Pathology in PINK1 Knockout Rats. International Journal of Molecular Sciences. 24. 690. 10.3390/ijms24010690 - Patented pharmaceutical technology against LewyBody dementia Parkinson's disease                                                                                                    US11612583B2: "Disease modifying methods for treating neurodegenerative diseases using nootropic agents" Raul Y Dagda, and Ruben K. Dagda - National Science foundation I-corps awards to CNS Curative Technologies: Patients interviews for medical necessities for NeuroClimax development https://www.nsf.gov/awardsearch/showAward?AWD_ID=2135052        4.- Vazquez-Mayorga E, Grigoruta M, Dagda R, Martinez B, Dagda RK. Intraperitoneal  Administration of Forskolin Reverses Motor Symptoms and Loss of Midbrain        Dopamine Neurons in PINK1 Knockout Rats. J Parkinson's Dis. 2022;12(3):831-850. doi:        10.3233/JPD-213016. PMID34957950; Third party studies of the ingredients            5.- PMCID: PMC9108570. Soman SK, Tingle D, Dagda RY, Torres M, Dagda M, Dagda RK. Cleaved PINK1 induces neuronal plasticity through PKA-mediated BDNF functional regulation. J Neurosci Res. 2021 Sep;99(9):2134-2155. doi: 10.1002/jnr.24854. Epub 2021 May 27. PMID: 34046942; PMCID: PMC8513622.   6.- Swain, M., Dagda, RY, Soman, S., Tapia, K., Dagda, RK.K. Brain-Derived Neurotrophic Factor protects neurons by stimulating mitochondrial function through Protein Kinase A, 2023, In-Press, Journal of Neurochemistry  7.- Seamon KB, Padgett W., Daly JW Forskolin unique diterpene activator of adenylate cyclase in membranes and in intact cells. Proc. Natl. Acad. Sci. USA. 1981;78:3363–3367. doi: 10.1073/pnas.78.6.3363.  8.- Owona BA, Zug C., Schluesener HJ, Zhang ZY Protective Effects of Forskolin on Behavioral Deficits and Neuropathological Changes in a Mouse Model of Cerebral Amyloidosis. J. Neuropathol. Exp. Neurol. 2016;75:618–627. doi: 10.1093/jnen/nlw043. 9.- Sangeetha S., Samanta MK, Manjunatha N., Tiwari S. Establishment of Pharmacokinetic Parameters for the Herbal Drug Containing Forskolin. J. Pharm. Res. 2011;4:2303–2306. ### Cognitive Decline Home Understanding Cognitive Decline Cognitive decline refers to the gradual deterioration of cognitive abilities, affecting memory, thinking, and reasoning. Recognizing early signs is crucial for timely intervention and improved quality of life. Common Causes of Cognitive Decline Conditions like Alzheimer's disease, vascular dementia, and mild cognitive impairment are primary contributors to cognitive decline. Each condition presents unique challenges that require specific management approaches, especially in dementia care Nevada. Cognitive Decline Test Online Take control of your cognitive health with cognitive decline test online. This comprehensive, easy-to-use test helps you identify early signs of cognitive decline from the comfort of your home. Early diagnosis can lead to more effective intervention and management. Begin your path towards better brain health today. Managing Cognitive Decline Disease Living with cognitive decline disease in Nevada requires medication to prevent it. We offer scientifically validated intranasal nutraceuticals and develop intranasal-delivered therapeutics to treat brain neurodegenerative diseases. Boosting Cognitive Function with Cognitive Boosters in Nevada Explore our pioneering approach to cognitive enhancement with NeuroClimax®. It is designed for patients with cognitive decline and related conditions, our intranasal nutraceuticals offer targeted support for improving brain health and function.The science and technology NeuroClimax's pre-clinical articles - Ruben & Dagda, Raul & Mayorga, Emmanuel & Martinez, Bridget & Gallahue, Aine. (2022). Intranasal Administration of Forskolin and Noopept Reverses Parkinsonian Pathology in PINK1 Knockout Rats. International Journal of Molecular Sciences. 24. 690. 10.3390/ijms24010690 - Patented pharmaceutical technology against LewyBody dementia Parkinson's disease                                                                                                    US11612583B2: "Disease modifying methods for treating neurodegenerative diseases using nootropic agents" Raul Y Dagda, and Ruben K. Dagda - National Science foundation I-corps awards to CNS Curative Technologies: Patients interviews for medical necessities for NeuroClimax development https://www.nsf.gov/awardsearch/showAward?AWD_ID=2135052        4.- Vazquez-Mayorga E, Grigoruta M, Dagda R, Martinez B, Dagda RK. Intraperitoneal  Administration of Forskolin Reverses Motor Symptoms and Loss of Midbrain        Dopamine Neurons in PINK1 Knockout Rats. J Parkinson's Dis. 2022;12(3):831-850. doi:        10.3233/JPD-213016. PMID34957950; Third party studies of the ingredients            5.- PMCID: PMC9108570. Soman SK, Tingle D, Dagda RY, Torres M, Dagda M, Dagda RK. Cleaved PINK1 induces neuronal plasticity through PKA-mediated BDNF functional regulation. J Neurosci Res. 2021 Sep;99(9):2134-2155. doi: 10.1002/jnr.24854. Epub 2021 May 27. PMID: 34046942; PMCID: PMC8513622.   6.- Swain, M., Dagda, RY, Soman, S., Tapia, K., Dagda, RK.K. Brain-Derived Neurotrophic Factor protects neurons by stimulating mitochondrial function through Protein Kinase A, 2023, In-Press, Journal of Neurochemistry  7.- Seamon KB, Padgett W., Daly JW Forskolin unique diterpene activator of adenylate cyclase in membranes and in intact cells. Proc. Natl. Acad. Sci. USA. 1981;78:3363–3367. doi: 10.1073/pnas.78.6.3363.  8.- Owona BA, Zug C., Schluesener HJ, Zhang ZY Protective Effects of Forskolin on Behavioral Deficits and Neuropathological Changes in a Mouse Model of Cerebral Amyloidosis. J. Neuropathol. Exp. Neurol. 2016;75:618–627. doi: 10.1093/jnen/nlw043. 9.- Sangeetha S., Samanta MK, Manjunatha N., Tiwari S. Establishment of Pharmacokinetic Parameters for the Herbal Drug Containing Forskolin. J. Pharm. Res. 2011;4:2303–2306. 10.-Costa, A., et al. Front Behav Neurosci, 2015.  11.-Costa, A., et al. Front Behav Neurosci, 2015. 9:253. 12.-Dagda, R.K., Das Banerjee, T. Rev Neurosci, 2015. 26(3):359-70. 13.-Hertz, N.T., et al. Cell, 2013. 154(4):737-47. 14.-Soman, S.K., et al. J Neurosci Res, 2021. 99(9):2134-2155. 15.-Ostrovskaya, R.U., et al. Bull Exp Biol Med, 2008. 146(3):334-7. 16.-Marcer, D., Hopkins, S.M. Age Ageing, 1977. 6(2):123-31. ### Products Home Intranasal Nootropic Spray Discover the future of cognitive enhancement with our Intranasal Nootropic Spray. Designed for optimal brain function, this revolutionary product sets a new standard in nootropic solutions. NeuroClimax® Our Intranasal nootropic sprays utilize a state-of-the-art intranasal nootropic formulation, ensuring rapid and effective absorption. This GMP-grade product is crafted with the highest standards to support cognitive health, improve focus, and enhance memory. In addition, our flagship product, NeuroClimax®, offers an unparalleled boost to cognitive performance and overall brain wellness. Read more NeuroClimax Gold nootropic formulation spray - Increase brain energy against brain fog and brain fatigue Our proprietary formula blends four powerful active compounds that synergistically restore brain energy, protect neurons, and enhance mental performance:• Kinetin – Awakens PINK1 neuroprotective pathways, stimulating BDNF production for neuron repair and survival [Hertz et al., 2013; Soman et al., 2021].• Noopept  – Improves learning, memory, and synaptic plasticity by activating TrkB and AMPA receptors, promoting cognitive resilience [Ostrovskaya et al., 2008].• Centrophenoxine – Enhances acetylcholine levels, improving short-term memory, focus, and mental clarity [Marcer & Hopkins, 1977]. Through direct-to-brain delivery, NeuroClimX MD achieves unattainable results with oral supplements that suffer from poor absorption and limited brain penetration. Benefits of NeuroClimX MD™• Restores BDNF levels to support neuroplasticity and brain regeneration • Recharges brain energy by enhancing mitochondrial function• Sharpens focus and memory for peak cognitive performance • Protects against neurodegeneration caused by oxidative stress and aging High brain bioavailability- Most brain supplements fail to cross the blood-brain barrier, limiting their effectiveness. NeuroClimX MD’s advanced purified organic grade nasal spray technology bypasses this barrier, delivering active compounds directly to the brain within seconds, ensuring maximum potency and targeted action with organic excipients such as soothers, emulsifiers, preservatives for sterility and preservation, and cyclodextrans.Who Can Benefit• Adults struggling with brain fog and mental fatigue• Individuals at risk of age-related cognitive decline• Professionals seeking enhanced focus and productivity• Individuals with mild cognitive impairment (MCI) or early signs of cognitive decline. Shop NeuroClimax Advanced nasal nootropic formulation spray The formulation spray has proprietary cognitive enhancer nootropic compounds with organic pharmaceutical grade active ingredients. It potentiates memory, learning, cognitive enhancement, brain energy and focus through brain plasticity mechanisms in neurons. Nasal spray formulation increases the level of Cyclic AMP, Brain-Derived Neurotrophic Factor and Nerve Growth Factor, thus the increase brain energy by increasing the level of ATP, increase the formation of neuronal networks and circuits, and activate neuronal re-development and growth of new neurons by NGF. Active ingredients: 99 percent pharmaceutical grade Cyclic AMP enhancers enantomiers + forskolin(up to 0.5 %), 99 percent pharmaceutical grade glutaminergic agonists of memory receptors peptides (up to 0.05%), Enhanced batch active ingredients added: Centrophenoxin Cholinergic potentiator (up to 1.7%). Excipient: soothers, preservatives, and high brain availability active ingredients concentrators (natural gamma Cyclodextrins) Shop Benefits Of NeuroClimax® Enhanced Cognitive Function Boost your brain's performance with improved clarity and focus. Quick Absorption Our intranasal delivery ensures the nootropic is quickly absorbed, providing fast-acting benefits. Scientifically Validated Backed by research, our formulation offers proven results in cognitive enhancement. Testimonials Here’s what our clients are saying about us. The NeuroClimax® has transformed my productivity. I feel sharper and more focused throughout the day. John D. NeuroClimax® is the best cognitive enhancer I've tried. The quick absorption is highly effective. Sarah L. Highly recommend NeuroClimax® for anyone looking to boost their brainpower. - Michael R. It has significantly improved my cognitive function and overall mental clarity. Emily W. Posted on Bart Fisher Trustindex verifies that the original source of the review is Google. My wife was diagnosed with brain disorders (Alzheimer's), 3 years ago, and I have used every supplement and peptide I can find to slow the progress of her disease. The CNS product seems to have been one of the only products we have tried that makes a difference. She is not cured at all, but the rate of decline has slowed to a degree that it is noticeable. We will continue using it in hopes that the effects are cumulative. Posted on Χρήστος Τσεκούρας Trustindex verifies that the original source of the review is Google. I tried Neuroclimax with different neurological patients and was really helpful. Most of them improved their motor and cognitive skills after a few days of use without any side effect. For me is a state of art medical product that really could change the life of people with brain disorders. Posted on Karim D. Saenzpardo Trustindex verifies that the original source of the review is Google. I took the product for over five weeks for one dose a day (one pump per nostril). I can confidently express that the product is fast acting, it improves my mood in the morning, increases my focus and mental acuity and productivity within 20 minutes of taking it. Once a day was enough but it help me get my mornings going!! It has also helped my sleep and OK to take it at night, so it does not seem to be a stimulant. Posted on miguel macias Trustindex verifies that the original source of the review is Google. NeuroClimax is a drug made usefull for those how needs focus and try to elevates from my quick tendency and manage to put me in a comfortable, focused, needed in my symptoms, as the fist times I've used it it does have a euphoric feeling, but when used normally u will lose the feeling but retain the focus that I need to be persistent at my task and everyday living without having to be scrambled on what to do. Posted on Pablito Junior Trustindex verifies that the original source of the review is Google. Very good customer service and recommended Posted on Raul Dagda Trustindex verifies that the original source of the review is Google. Realmente me sorprendio al usar Neuro Clímax, logré un enfoque perfecto y una mayor capacidad y habilidad de pensamiento para tomar desiciones complejas y urgentes, y además un agradable estado de ánimo qué me motiva a tomar la iniciativa sobre pendientes importantes que fui posponiendo Felicito a CNS por el desarrollo científico de Neuroclimax por pensar en el bienestar de nuestro cerebro y cuerpo Posted on Feliciano Velazquez Trustindex verifies that the original source of the review is Google. Take it constantly and the product does help it really works Posted on Cesar Eduardo Trustindex verifies that the original source of the review is Google. Good products, thank you very much Posted on Alvaro Pastrana Trustindex verifies that the original source of the review is Google. Amabilidad Reach Your Potential with NeuroClimax® – Shop Now and Experience Enhanced Brain Function Today! Contact Us ### Contact Contact Us Home Contact OUR DETAILS Contact Information Book a call Headquarter offices and manufacturing site CNS Curative Technologies, LLC 300 East 2nd street 15th floor, 1510, suite 1512 Reno, Nevada, 89501 Get Directions Email contact@cnscurative.com Email Now GET IN TOUCH Write a Message to Experts (775) 376-0613 300 East 2nd street, 15th floor, 1510, suite 1512, Reno, Nevada, 89501 Facebook-f Twitter Linkedin-in ### About Home ABOUT US At CNS Curative Technologies, we lead the frontier in neuroscience innovation, specializing in intranasal therapeutics for neurological disorders. With a foundation in rigorous research and GMP-grade manufacturing, we develop effective solutions like NeuroClimax® to enhance brain health and benefits for motor symptoms (Basal Ganglia, and immuno-inflammation related symptoms) and cognitive decline related to brain aging and neurometabolic difficiencies . Committed to advancing neurology care in Nevada and beyond, we forge partnerships and leverage scientific excellence to enhance lives through groundbreaking pharmaceutical technologies. Expanding Horizons with NeuroClimax®We are proud to develop and manufacture our first pharmaceutical-grade nootropic, NeuroClimax®. Utilizing state-of-the-art facilities clean room manufacturing facilities, we aim for large-scale production. Collaborating with clinics, we offer NeuroClimax® to neurological patients with motor symptoms, and cognitive decline, enhancing their quality of life through innovative solutions. Our Commitment to Innovation and ResearchWith significant support through community, foundation, and government grants, we've partnered with the University of Nevada, Reno School of Medicine. Our mission is to bridge unmet medical needs by developing advanced intranasal delivery technologies. Our collaborations have resulted in over ten research publications and substantial funding. Our VisionOur vision at CNS Curative Technologies is to redefine neurology through innovative and effective treatments. By leveraging advanced research and GMP-grade manufacturing, we aim to pioneer breakthroughs in brain health. We envision a future where our products, like NeuroClimax®, lead the industry in improving cognitive function and enhancing quality of life for individuals affected by neurological disorders worldwide. Our MissionAt CNS Curative Technologies, our mission is to revolutionize neurological care through scientific innovation and compassionate service. We strive to develop and deliver cutting-edge intranasal therapeutics that effectively treat and manage neurological disorders such as Progressive Supranuclear Palsy, Amyotrophic lateral sclerosis (ALS), and cognitive decline. By prioritizing research excellence and patient well-being, we aim to empower individuals to achieve optimal brain health and wellness. https://www.youtube.com/watch?v=-j_HgxP3HnwOUR STAFF Our Team Members Raul Dagda, M.S.CEO & Co-founder rauld@cnscurative.com Ruben K. Dagda, PhDChief Scientific Officer & Co-founder rkdagda@cnscurative.com Dr. Bridget MartinezClinical liason & Advisor Jasmin GomezBusiness Development & Account Manager JasminGomez@cnscurative.com Aine Gallahue, MsciSecond clinical liason & MD resident Prioritize Brain Wellness With Neuroclimax® Today Contact Us ### Home Facebook-f Twitter Linkedin-in Pioneering Advancements in brain health against cognitive decline and neurodegeneration Optimize brain neurotrophic signaling for peak cognitive and memory performance The cognitive health market has long been dominated by stimulants, caffeine, metabolic enhancers, and conventional nootropics that primarily aim to provide temporary increases in alertness or mental energy. While these products may offer short-term cognitive support, they often do not address the biological processes that help maintain healthy brain function over time.   CNS Curative Technologies is pioneering a different approach. Our proprietary, patent-protected intranasal nootropic formulations sprays are built on the principle that supporting the brain's natural biological signaling pathways is fundamental to long-term cognitive wellness and reduce cognitive decline in people affected with brain degenerative diseases. Rather than relying on temporary stimulation, our formulations utilize highly purified active nootropic ingredients delivered through the intranasal pathway to support neurotrophic signaling, neuronal communication, and the brain's natural capacity for neuroplasticity. Our technology is protected by proprietary intellectual property and supported by preclinical research and scientific data that guide the design of our formulations. This research-first approach enables us to develop innovative products that target the biological foundations of cognitive function before focusing on enhancing mental energy or performance. Why Our Platform Is Different   Patented technology protecting our proprietary intranasal nootropic platform. Science-driven innovation supported by proprietary research and experimental data. Intranasal delivery designed to efficiently deliver highly purified active nootropic ingredients. Supports neurotrophic signaling associated with healthy neuronal function (cognitive support, working memory and memory retrieval) Supports neuroplasticity, the brain's natural ability to adapt, reorganize, and maintain healthy neural networks. Non-stimulant approach focused on supporting brain energy efficiency rather than relying on temporary stimulation,  We believe the future of cognitive wellness lies in supporting the biological mechanisms that contribute to resilient brain function. Our mission is to translate cutting-edge neuroscience into innovative, evidence-informed solutions that help redefine what cognitive support can be. Experience the next generation of patented neuroscience-driven cognitive wellness.     Discover More Revolutionizing Minds, Restoring Lives  State of the art technologies on intranasal nootropics and therapeutics for enhanced brain wellness. Experience the future of brain health with our scientifically validated products.https://www.youtube.com/watch?v=-j_HgxP3Hnw Start your brain health benefits today with NeuroClimax® Reach the potential of your mind with NeuroClimax®    Up to 50% off in monthly subscription, pay later, money back warrantied  Shop now USDA certified third party laboratory safety analysis on metal free and sterility of each batch Enhanced Cognitive Function NeuroClimax® boosts cognitive function, enhancing memory, focus, and mental clarity through rapid intranasal absorption. Safe and Scientifically Validated NeuroClimax® is GMP-grade and scientifically validated, ensuring safe and effective cognitive enhancement without harmful side effects. Convenient and User-Friendly NeuroClimax® intranasal spray is portable and easy to use, offering convenient cognitive support wherever you go. NeuroClimax family of intranasal formulation nootropic sprays NeuroClimax's product performance on customers Learn more We offer intranasal nootropic sprays aimed at neurotrophic signaling support with organic pharmaceutical grade active ingredients. Our NeuroClimax advanced spray potentiates memory, learning, cognitive enhancement, brain energy and focus through brain plasticity mechanisms in neurons. Nasal spray formulation increases the level of Cyclic AMP, Brain-Derived Neurotrophic Factor and Nerve Growth Factor, thus the increase brain energy by increasing the level of ATP, increase the formation of neuronal networks and circuits, and activate neuronal re-development and growth of new neurons by NGF.  Active ingredients: 99 percent pharmaceutical grade Cyclic AMP enhancers (up to 0.5 %), and 99 percent pharmaceutical grade noopept,  (up to 0.05%). NeuroClimax Gold intranasal formulation nootropic spray offers neurotrophic support for more acute brain energy and executive working memory cognitive enhancement through brain plasticity mechanisms , and high brain availibility of acetylcholine. Active ingredients: 99% kinetin pharmaceutical active ingredients (up to 1.09%), 99% centrophenoxin, and  and 99 percent pharmaceutical grade noopept,  (up to 0.05%). Excipient: soothers, preservatives, and high brain availability active ingredients concentrators (natural gamma Cyclodextrans). About CNS Curative Technologies At CNS Curative Technologies, we are dedicated to enhancing brain wellness through innovative intranasal nootropics and therapeutics. Our mission is to revolutionize brain health by offering solutions grounded in rigorous scientific research. Partnering with neurology clinics of Nevada and leveraging our collaborations with top institutions, we aim to transform the field of Nevada neurologic care. Read more Research and Innovation Leading the Way in Brain Health Research At CNS Curative Technologies, we are at the forefront of brain health research. Our collaboration with the Whittermore Petterson institute, the Whittermore Investment Group in Reno Nevada, and other prestigious institutions (Parkinson's Disease Foundation) enables us to develop groundbreaking treatments. We are committed to advancing Nevada neurologic care through innovative research and clinical trials. 0 products in the Pipeline, 3 launched products 0 + Satisfied Clients 0 products in the Pipeline 1 launched product 0 + Satisfied Clients Recent developments on NeuroClimax's science and technology CNS Curative Technologies partners with Gym for the BrainGym for the Brain adds NeuroClimax® to Session Protocol Ascend 2.0 business development grant for advanced development of formulationDr. Ruben Dagda of the University of Reno Nevada Selected for ASCEND2.0 Program to Advance Parkinson’s Disease Research CNS Curative Technologies files patent for treatment of cognitive decline due to brain fog, and brain fatigue U.S. Provisional Patent Application No. 63/897,520Title: TREATMENT OF COGNITIVE DECLINE AND FATIGUE WITH INTRANASAL NOOTROPIC FORMULATIONSFirst Named Inventor: Raul Y. DagdaCNS Curative Technologies LLCRef.: FHW081752 Award Abstract # 2135052I-Corps: Drug delivery systems for treating degenerative brain diseases NSF I-Corps | NSF SBIRPreclinical science publications: CNS / CT 001 intranasal nootropic formulations increase neurotropic signaling for regenerative brain repair mechanisms, new neuronal growth, and eliminating brain aggregates in brains of genetic rodent models of Parkinson's disease.Intranasal Administration of Forskolin and Noopept Reverses Parkinsonian Pathology in PINK1 Knockout Rats - PMCIntraperitoneal administration of nootropic compounds in models of Parkinson's diseaseIntranasal Administration of Forskolin and Noopept Reverses Parkinsonian Pathology in PINK1 Knockout Rats  Nurse association health awareness podcast Click here for: Maintaining your Brain Health podcast with CNS Curative Technologies, LLC Why Choose Us? 92.85% of clients reported 1 benefit Customized therapies for optimum results and personalized care. 78.57% of clients reported 2 benefits Leading in innovative therapies, backed by extensive clinical research and development. 64% of clients reported increased focus 1 hour Holistic care approach ensuring well-rounded support and patient satisfaction. 71% of clients increased energy 1 hour Customized therapies for optimum results and personalized care. 50% of clients reported more productivity Leading in innovative therapies, backed by extensive clinical research and development. 50% with motor symptom patients showed improvements in movement Partnerships with clinics and community organizations Fisiokinesis at Greece Athens adds NeuroClimax, NeuroClimax Advanced nootropic formulation, and NeuroClimX MD into their clinical protocols Click here Testimonials Here’s what our clients are saying about us. Using NeuroClimax® has transformed my mornings. I feel more alert and energized throughout the day, with noticeable improvements in my memory and mood. A fantastic product for brain wellness! Michael S. I've struggled with brain fog for years, but NeuroClimax® has helped clear it up remarkably. I feel sharper and more capable in my daily tasks. Thank you, CNS Curative Technologies! Emily L. As someone managing Parkinson's disease, NeuroClimax® has provided much-needed relief. It's helped reduce my symptoms and enhance my overall well-being. I'm grateful for this innovative solution. David P. Posted on Bart Fisher Trustindex verifies that the original source of the review is Google. My wife was diagnosed with brain disorders (Alzheimer's), 3 years ago, and I have used every supplement and peptide I can find to slow the progress of her disease. The CNS product seems to have been one of the only products we have tried that makes a difference. She is not cured at all, but the rate of decline has slowed to a degree that it is noticeable. We will continue using it in hopes that the effects are cumulative. Posted on Χρήστος Τσεκούρας Trustindex verifies that the original source of the review is Google. I tried Neuroclimax with different neurological patients and was really helpful. Most of them improved their motor and cognitive skills after a few days of use without any side effect. For me is a state of art medical product that really could change the life of people with brain disorders. Posted on Karim D. Saenzpardo Trustindex verifies that the original source of the review is Google. I took the product for over five weeks for one dose a day (one pump per nostril). I can confidently express that the product is fast acting, it improves my mood in the morning, increases my focus and mental acuity and productivity within 20 minutes of taking it. Once a day was enough but it help me get my mornings going!! It has also helped my sleep and OK to take it at night, so it does not seem to be a stimulant. Posted on miguel macias Trustindex verifies that the original source of the review is Google. NeuroClimax is a drug made usefull for those how needs focus and try to elevates from my quick tendency and manage to put me in a comfortable, focused, needed in my symptoms, as the fist times I've used it it does have a euphoric feeling, but when used normally u will lose the feeling but retain the focus that I need to be persistent at my task and everyday living without having to be scrambled on what to do. Posted on Pablito Junior Trustindex verifies that the original source of the review is Google. Very good customer service and recommended Posted on Raul Dagda Trustindex verifies that the original source of the review is Google. Realmente me sorprendio al usar Neuro Clímax, logré un enfoque perfecto y una mayor capacidad y habilidad de pensamiento para tomar desiciones complejas y urgentes, y además un agradable estado de ánimo qué me motiva a tomar la iniciativa sobre pendientes importantes que fui posponiendo Felicito a CNS por el desarrollo científico de Neuroclimax por pensar en el bienestar de nuestro cerebro y cuerpo Posted on Feliciano Velazquez Trustindex verifies that the original source of the review is Google. Take it constantly and the product does help it really works Posted on Cesar Eduardo Trustindex verifies that the original source of the review is Google. Good products, thank you very much Posted on Alvaro Pastrana Trustindex verifies that the original source of the review is Google. Amabilidad Prioritize Brain Wellness With Neuroclimax® Today Contact Us ## My Templates ### Elementor Single Product #713 view products Taxes included. 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Let's Make Something Great Together Contact Us ### Footer Facebook-f Twitter Linkedin-in Useful Links Home About Services Projects Contact us Our Services Robotic Automation Predictive Analysis Machine Learning Data Security IT Management Contact US +61 3 8376 6284 Info@divergeai.com 21 King Street Melbourne, 3000, Australia Copyright 2022, DivergeAI.com All Rights Reserved. ### Footer Facebook-f Twitter Linkedin-in Useful Links Home About Products Order Contact us Our Services Cognitive Decline Parkinson's Disease Wellness & Aging Market insights Contact US contact@cnscurative.com 300 East 2nd street, 15th floor, 1510, suite 1512, Reno, Nevada, 89501 Disclaimer: NeuroClimax Intranasal nootropic sprays are not approved by the FDA to diagnose, indicate and treat diseases.Copyright 2025, All Copy Rights Reserved. ### Header Let's Talk ### Header Home About Products Science Cognitive Decline Parkinson’s Disease Wellness & Aging Order Investors Market insights and Product Pipeline Legal Lyme Disease Locations X Contact ### Kit Styles: Diverge ### Default Kit ## Products ### NeuroClimax Gold Nootropic formulation spray - Brain metabolic enhancer Our proprietary formula blends three powerful active compounds that synergistically restore brain energy, protect neurons, and enhance mental performance: • Kinetin 99% pure up to 1.09% (w/v) – Awakens PINK1 neuroprotective pathways, stimulating BDNF production for neuron repair and survival [Hertz et al., 2013; Soman et al., 2021]. • Noopept 99% pure up to 0.05% (w/v) – Improves learning, memory, and synaptic plasticity by activating TrkB and AMPA receptors, promoting cognitive resilience [Ostrovskaya et al., 2008]. • Centrophenoxine 99% pure up to 0.37% (w/v) Enhances acetylcholine levels, improving short-term memory, focus, and mental clarity [Marcer & Hopkins, 1977]. Through direct-to-brain delivery, NeuroClimax Gold achieves unattainable results with oral supplements that suffer from poor absorption and limited brain penetration. Benefits of NeuroClimax Gold™ • Restores BDNF levels to support neuroplasticity and brain regeneration • Recharges brain energy by enhancing mitochondrial function • Sharpens focus and memory for peak cognitive performance • Protects against neurodegeneration caused by oxidative stress and aging High brain bioavailability- Most brain supplements fail to cross the blood-brain barrier, limiting their effectiveness. NeuroClimax Gold’s advanced purified organic grade nasal spray technology bypasses this barrier, delivering active compounds directly to the brain within seconds, ensuring maximum potency and targeted action with organic excipients such as soothers, emulsifiers, preservatives for sterility and preservation, and cyclodextrans. Who Can Benefit • Adults struggling with brain fog and mental fatigue • Individuals at risk of age-related cognitive decline • Professionals seeking enhanced focus and productivity • Individuals with mild cognitive impairment (MCI) or early signs of cognitive decline. ### NeuroClimax Gold - modified - intranasal nootropic formulation spray Our proprietary formula blends three powerful active compounds that synergistically restore brain energy, protect neurons, and enhance mental performance. We can modify NeuroClimax Gold intranasal nootropic formulation spray to fit your brain health priorities with concentrated customizable choice of active ingredients such as kinetin for priority on neuronal energy and metabolic enhancer. • Kinetin 99% pure up to 1.09% (w/v) – Awakens PINK1 neuroprotective pathways, stimulating BDNF production for neuron repair and survival [Hertz et al., 2013; Soman et al., 2021]. • Noopept 99% pure up to 0.05% (w/v) – Improves learning, memory, and synaptic plasticity by activating TrkB and AMPA receptors, promoting cognitive resilience [Ostrovskaya et al., 2008]. • Centrophenoxine 99% pure up to 0.37% (w/v) – Enhances acetylcholine levels, improving short-term memory, focus, and mental clarity [Marcer & Hopkins, 1977]. Through direct-to-brain delivery, NeuroClimax Gold achieves unattainable results with oral supplements that suffer from poor absorption and limited brain penetration. Benefits of NeuroClimax Gold™ • Restores BDNF levels to support neuroplasticity and brain regeneration • Recharges brain energy by enhancing mitochondrial function • Sharpens focus and memory for peak cognitive performance • Protects against neurodegeneration caused by oxidative stress and aging High brain bioavailability- Most brain supplements fail to cross the blood-brain barrier, limiting their effectiveness. NeuroClimax Gold’s advanced purified organic grade nasal spray technology bypasses this barrier, delivering active compounds directly to the brain within seconds, ensuring maximum potency and targeted action with organic excipients such as soothers, emulsifiers, preservatives for sterility and preservation, and cyclodextrans. Excipients: soothers, preservatives, and high brain availability active ingredients concentrators (natural gamma Cyclodextrins) in sterile PBS, ph 7.3 Who Can Benefit • Adults struggling with brain fog and mental fatigue • Individuals at risk of age-related cognitive decline • Professionals seeking enhanced focus and productivity • Individuals with mild cognitive impairment (MCI) or early signs of cognitive decline. ### NeuroClimax Advanced intranasal nootropic formulation spray - regenerative memory and cognitive performance Nootropic formulation spray brain enhancer with organic pharmaceutical grade active ingredients: Cyclic amp enhancers for regenerative memory, learning and executive brain neurogenic stimulation by nootropics and brain peptides in sterile pbs with excipients. 99 percent pharmaceutical grade Cyclic AMP enhancer and forskolin enantiomers (0.5 percent volume to weight maximum) 99 percent pharmaceutical grade Noopept (0.05 percent volume to weight maximum) Excipients blends give direct brain targeting, high brain bioavailability, and potentiation of active pharmaceutical grade active ingredients with soothers for convenience dosing. Each two sprays give up to 0.5% of active ingredients     Logo, CNS Curative Technologies, and NeuroClimax are registered trademarks pertaining to CNS Curative Technologies with trademark registration numbers: 98309088, 98309099, 98309108 Made and manufacture by CNS Curative Technologies Manufactured and developed in state-of-the-art clean room facilities http://www.cnscurative.com Not evaluated by FDA to label, indicate, or treat diseases.